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USP14 抗体

USP14 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 9C1 unconjugated
产品编号 ABIN4915065
发货至: 中国
  • 抗原 See all USP14 抗体
    USP14 (Ubiquitin Specific Peptidase 14 (USP14))
    适用
    • 59
    • 8
    • 8
    • 4
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 8
    小鼠
    克隆类型
    • 43
    • 16
    单克隆
    标记
    • 31
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP14 antibody is un-conjugated
    应用范围
    • 41
    • 25
    • 13
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    Purified His-tagged USP14 protein was used to produced this monoclonal antibody.
    克隆位点
    9C1
    亚型
    IgG1
    Top Product
    Discover our top product USP14 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    USP14 (Ubiquitin Specific Peptidase 14 (USP14))
    别名
    USP14 (USP14 产品)
    背景

    Synonyms: TGT, Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14

    Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

    基因ID
    9097
    UniProt
    P54578
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