SNX6 抗体
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- 抗原 See all SNX6 抗体
- SNX6 (Sorting Nexin 6 (SNX6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SNX6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- 免疫原
- This SNX6 monoclonal antibody is generated from mouse immunized with SNX6 recombinant protein.
- 克隆位点
- 5T6
- 亚型
- IgG1
- Top Product
- Discover our top product SNX6 Primary Antibody
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SNX6 (Sorting Nexin 6 (SNX6))
- 别名
- SNX6 (SNX6 产品)
- 别名
- MGC75952 antibody, MGC80251 antibody, im:7146294 antibody, wu:fa55b10 antibody, zgc:110798 antibody, MSTP010 antibody, TFAF2 antibody, 2010006G21Rik antibody, 2610032J07Rik antibody, 2810425K19Rik antibody, AU018928 antibody, C85963 antibody, sorting nexin 6 antibody, sorting nexin 6 L homeolog antibody, snx6 antibody, snx6.L antibody, SNX6 antibody, Snx6 antibody
- 背景
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Synonyms: TFAF2, MSTP010, Sorting nexin-6, TRAF4-associated factor 2, SNX6
Background: Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Does not have in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R (PubMed:17148574). May function as link between transport vesicles and dynactin (Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network (PubMed:20354142). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation (PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B (By similarity). May contribute to transcription regulation (Probable).
- 基因ID
- 58533
- UniProt
- Q9UNH7
- 途径
- EGFR Signaling Pathway
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