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MMP14 抗体

MMP14 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 3A6 unconjugated
产品编号 ABIN4911994
发货至: 中国
  • 抗原 See all MMP14 抗体
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    适用
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    宿主
    • 72
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    小鼠
    克隆类型
    • 63
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    单克隆
    标记
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    This MMP14 antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    交叉反应
    纯化方法
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14.
    克隆位点
    3A6
    亚型
    IgM
    Top Product
    Discover our top product MMP14 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IF()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    别名
    MMP14 (MMP14 产品)
    背景

    Synonyms: MMP-14, MMP-X1, MT-MMP, MT1MMP, MTMMP1, WNCHRS, MT1-MMP, MT-MMP 1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14

    Background: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

    基因ID
    4323
    UniProt
    P50281
    途径
    Autophagy
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