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MGMT 抗体

MGMT 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated
产品编号 ABIN4911931
发货至: 中国
  • 抗原 See all MGMT 抗体
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    适用
    • 71
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 69
    • 9
    小鼠
    克隆类型
    • 62
    • 16
    单克隆
    标记
    • 43
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MGMT antibody is un-conjugated
    应用范围
    • 53
    • 33
    • 20
    • 20
    • 13
    • 13
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
    克隆位点
    4C12
    亚型
    IgG1
    Top Product
    Discover our top product MGMT Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    别名
    MGMT (MGMT 产品)
    别名
    AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
    背景

    Synonyms: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    基因ID
    4255
    UniProt
    P16455
    途径
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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