MBD3 抗体
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- 抗原 See all MBD3 抗体
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MBD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- Purified His-tagged MBD3 protein was used to produced this monoclonal antibody.
- 克隆位点
- 5C3
- 亚型
- IgG1
- Top Product
- Discover our top product MBD3 Primary Antibody
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- 别名
- MBD3 (MBD3 产品)
- 别名
- xmbd3 antibody, MGC69548 antibody, MBD3 antibody, DKFZp459N1635 antibody, AI181826 antibody, AU019209 antibody, methyl-CpG binding domain protein 3 S homeolog antibody, methyl-CpG binding domain protein 3 antibody, mbd3.S antibody, mbd3 antibody, MBD3 antibody, Mbd3 antibody
- 背景
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Synonyms: Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3, MBD3
Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
- 基因ID
- 53615
- UniProt
- O95983
- 途径
- Chromatin Binding
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