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KAT5 抗体 (pSer90)

KAT5 适用: 小鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4911293
发货至: 中国
  • 抗原 See all KAT5 抗体
    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
    抗原表位
    • 17
    • 15
    • 12
    • 8
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer90
    适用
    • 85
    • 63
    • 55
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 100
    • 14
    克隆类型
    • 101
    • 14
    多克隆
    标记
    • 56
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This KAT5 antibody is un-conjugated
    应用范围
    • 84
    • 52
    • 26
    • 26
    • 23
    • 16
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthesised phosphopeptide derived from human KAT5 around the phosphorylation site of Ser90
    亚型
    IgG
    Top Product
    Discover our top product KAT5 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
    别名
    KAT5 (KAT5 产品)
    别名
    6121 antibody, CG6121 antibody, DmEG0007.7 antibody, Dmel/TIP60 antibody, Dmel\\CG6121 antibody, Dmel\\TIP60 antibody, EG0007.7 antibody, EG:EG0007.7 antibody, TIP60 antibody, dTIP60 antibody, dTip60 antibody, dmHAG405 antibody, im:6908768 antibody, wu:fb55b08 antibody, zgc:110752 antibody, ESA1 antibody, HTATIP antibody, HTATIP1 antibody, PLIP antibody, TIP antibody, ZC2HC5 antibody, cPLA2 antibody, AI839539 antibody, CPLA2 antibody, Htatip antibody, Htatip1 antibody, Tip55 antibody, Tip60 antibody, K(lysine) acetyltransferase 5a antibody, lysine acetyltransferase 5 antibody, Tat interactive protein 60kDa antibody, histone acetyltransferase Tip60 antibody, tip60, putative antibody, K(lysine) acetyltransferase 5b antibody, K(lysine) acetyltransferase 5 antibody, kat5a antibody, KAT5 antibody, Tip60 antibody, LOC413101 antibody, LOC5579231 antibody, Smp_053140 antibody, kat5b antibody, Kat5 antibody
    背景

    Synonyms: TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, ZC2HC5, HTATIP1, Histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, Histone acetyltransferase HTATIP, HIV-1 Tat interactive protein, Lysine acetyltransferase 5, cPLA(2)-interacting protein, KAT5

    Background: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2. Promotes FOXP3 acetylation and positively regulates its transcriptional repressor activity (PubMed:17360565).

    基因ID
    10524
    UniProt
    Q92993
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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