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HINT1 抗体

HINT1 适用: 人, 小鼠, 大鼠 WB, IF, IF (cc), IHC (p), FACS 宿主: 小鼠 Monoclonal 5C3 unconjugated
产品编号 ABIN4910644
发货至: 中国
  • 抗原 See all HINT1 抗体
    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
    适用
    • 49
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    人, 小鼠, 大鼠
    宿主
    • 46
    • 3
    小鼠
    克隆类型
    • 48
    • 1
    单克隆
    标记
    • 24
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    This HINT1 antibody is un-conjugated
    应用范围
    • 21
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    Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein G.
    免疫原
    This HINT1 antibody is generated from a mouse immunized with a recombinant protein of human HINT1.
    克隆位点
    5C3
    亚型
    IgG1
    Top Product
    Discover our top product HINT1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IF()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
    别名
    HINT1 (HINT1 产品)
    别名
    hint antibody, pkci-1 antibody, prkcnh1 antibody, HINT antibody, NMAN antibody, PKCI-1 antibody, PRKCNH1 antibody, AA673479 antibody, Hint antibody, Ipk1 antibody, Pkci antibody, Prkci antibody, zgc:103764 antibody, CHPKCI antibody, HINTZ antibody, PKCIZ antibody, histidine triad nucleotide binding protein 1 antibody, histidine triad nucleotide binding protein 1 S homeolog antibody, histidine triad nucleotide binding protein 1-Z antibody, Histidine triad nucleotide-binding protein 1 antibody, HINT1 antibody, hint1 antibody, Hint1 antibody, hint1.S antibody, HINT1Z antibody, hint-1 antibody
    背景

    Synonyms: HINT, NMAN, PKCI-1, PRKCNH1, Histidine triad nucleotide-binding protein 1, Adenosine 5'-monophosphoramidase, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, HINT1, PKCI1

    Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

    基因ID
    3094
    UniProt
    P49773
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