HINT1 抗体
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- 抗原 See all HINT1 抗体
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HINT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein G.
- 免疫原
- This HINT1 antibody is generated from a mouse immunized with a recombinant protein of human HINT1.
- 克隆位点
- 5C3
- 亚型
- IgG1
- Top Product
- Discover our top product HINT1 Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IF() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- 别名
- HINT1 (HINT1 产品)
- 别名
- hint antibody, pkci-1 antibody, prkcnh1 antibody, HINT antibody, NMAN antibody, PKCI-1 antibody, PRKCNH1 antibody, AA673479 antibody, Hint antibody, Ipk1 antibody, Pkci antibody, Prkci antibody, zgc:103764 antibody, CHPKCI antibody, HINTZ antibody, PKCIZ antibody, histidine triad nucleotide binding protein 1 antibody, histidine triad nucleotide binding protein 1 S homeolog antibody, histidine triad nucleotide binding protein 1-Z antibody, Histidine triad nucleotide-binding protein 1 antibody, HINT1 antibody, hint1 antibody, Hint1 antibody, hint1.S antibody, HINT1Z antibody, hint-1 antibody
- 背景
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Synonyms: HINT, NMAN, PKCI-1, PRKCNH1, Histidine triad nucleotide-binding protein 1, Adenosine 5'-monophosphoramidase, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, HINT1, PKCI1
Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
- 基因ID
- 3094
- UniProt
- P49773
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