COPS3 抗体 (AA 261-360)
Quick Overview for COPS3 抗体 (AA 261-360) (ABIN4908217)
抗原
See all COPS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-360
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human COPS3
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亚型
- IgG
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anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibody
COPS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibodyCOPS3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 194-423) antibodyCOPS3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibodyCOPS3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (C-Term) antibodyCOPS3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 139-390) antibodyCOPS3 适用: 人, 大鼠 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 194-423) antibodyCOPS3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (Center) antibodyCOPS3 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
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别名
- COPS3
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背景
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Synonyms: COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
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基因ID
- 8533
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途径
- Cell Division Cycle
抗原
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