NLRP3 抗体 (AA 81-93)
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- 抗原 See all NLRP3 抗体
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
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抗原表位
- AA 81-93
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适用
- 人, 猴
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This NLRP3 antibody is un-conjugated
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应用范围
- ELISA
- 特异性
- Human NLRP3. This antibody is expected to recognize all reported isoforms (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.
- 预测反应
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Panda, Bat, Pig (92%) Dog, Bovine, Rabbit (85%).
- 纯化方法
- Immunoaffinity purified
- 免疫原
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Synthetic peptide RDLYEKAKRDEPK-C from the N-terminus (near) of human NLRP3 (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Panda, Bat, Pig (92%), Dog, Bovine, Rabbit (85%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product NLRP3 Primary Antibody
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- 应用备注
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Approved: Peptide-ELISA (1:32000)
Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx 36 kDa band in Human Peripheral Blood Mononucleocytes lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the smallest calculated size of 106 kDa according to NP_899632.1. The 36 kDa band was successfully blocked by incubation with the immunizing peptide. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Minimize freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze-thaw cycles.
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- 抗原
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
- 别名
- NALP3 / NLRP3 (NLRP3 产品)
- 背景
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Name/Gene ID: NLRP3
Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS - 基因ID
- 114548
- NCBI登录号
- NP_004886, NP_899632, NP_001120933, NP_001120934
- UniProt
- Q96P20
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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