BBS4 抗体
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- 抗原 See all BBS4 抗体
- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BBS4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This BBS4 antibody is generated from a mice immunized with a recombinant protein between 1-240 amino acids from human BBS4.
- 克隆位点
- 2C8
- 亚型
- IgG1
- Top Product
- Discover our top product BBS4 Primary Antibody
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anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 350-519) antibody
BBS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 431-519) antibodyBBS4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-240) antibodyBBS4 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1292CT845-130-218 unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (N-Term) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibodyBBS4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 33-46) antibodyVerified BBS4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 125-139) antibodyVerified BBS4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 215-264) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 斑马鱼, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 71-120) antibodyBBS4 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
- 别名
- BBS4 (BBS4 产品)
- 别名
- CG13232 antibody, Dmel\\CG13232 antibody, zgc:152964 antibody, AW537059 antibody, AW742241 antibody, D9Ertd464e antibody, Bardet-Biedl syndrome 4 antibody, bardet-biedl syndrome 4 antibody, Bardet-Biedl syndrome 4 (human) antibody, BBS4 antibody, bbs4 antibody, Bbs4 antibody
- 背景
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Synonyms: Bardet-Biedl syndrome 4 protein, BBS4
Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.
- 基因ID
- 585
- UniProt
- Q96RK4
- 途径
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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