ATG3 抗体
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- 抗原 See all ATG3 抗体
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATG3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein G.
- 免疫原
- This ATG3 antibody is generated from a mouse immunized with recombinant protein of human ATG3.
- 克隆位点
- 7C2
- 亚型
- IgG1
- Top Product
- Discover our top product ATG3 Primary Antibody
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anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 7A1D1 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-314) antibodyATG3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 适用: 人, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 适用: 人, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (Middle Region) antibodyATG3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibody (PerCP)ATG3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-ATG3 Autophagy Related 3 (ATG3) antibody (APC)ATG3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibodyATG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibody (HRP)ATG3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-ATG3 Autophagy Related 3 (ATG3) antibody (Alkaline Phosphatase (AP))ATG3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
- 别名
- ATG3 (ATG3 产品)
- 别名
- atg3 antibody, im:6910145 antibody, wu:fb15g12 antibody, zgc:64156 antibody, APG3 antibody, APG3-LIKE antibody, APG3L antibody, PC3-96 antibody, 2610016C12Rik antibody, Apg3l antibody, Atg3l antibody, PIG-1 antibody, Pig1 antibody, ATATG3 antibody, K11J9.1 antibody, K11J9_1 antibody, autophagy related 3 antibody, autophagy 3 (APG3) antibody, similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy antibody, atg3 antibody, ATG3 antibody, Atg3 antibody
- 背景
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Synonyms: APG3, APG3L, PC3-96, APG3-LIKE, Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, hApg3, Protein PC3-96, ATG3
Background: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
- 基因ID
- 64422
- UniProt
- Q9NT62
- 途径
- Autophagy
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