tau 抗体 (AA 150-220)
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- 抗原 See all tau 抗体
- tau (tau Protein)
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抗原表位
- AA 150-220
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This tau antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Tau is a protein encoded by the MAPT gene which is approximately 78,9 kDa. Tau is localised to the cytoplasm and cell membrane. It is involved in the apoptotic cleavage of cellular proteins, MAPK signalling pathway, CDK-mediated phosphorylation and removal of Cdc6 and development slit-robo signalling. It promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein. Tau is expressed in neurons. Mutations in the MAPT gene may result in Frontotemporal dementia. STJ98827 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Tau protein.
- 特异性
- The antibody detects endogenous Tau.
- 产品特性
- Rabbit Polyclonal to Tau.
- 纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- 免疫原
- Synthetic peptide from human Tau protein.
- 亚型
- IgG
- Top Product
- Discover our top product tau Primary Antibody
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- 应用备注
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WB 1:500-2000
ELISA 1:5000-20000 - 说明
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Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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