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RAD51 抗体

RAD51 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 4H10-G5-H4 unconjugated
产品编号 ABIN4902204
发货至: 中国
  • 抗原 See all RAD51 抗体
    RAD51 (DNA Repair Protein Homolog 1 (RAD51))
    适用
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    人, 小鼠, 大鼠, 猴
    宿主
    • 107
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    小鼠
    克隆类型
    • 104
    • 24
    单克隆
    标记
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    This RAD51 antibody is un-conjugated
    应用范围
    • 88
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    Western Blotting (WB), ELISA
    原理
    Rad51 is a protein encoded by the RAD51 gene which is approximately 35 kDa. Rad51 is localised to the nucleus, cytoplasm and mitochondrion matirx. It is involved in the resolution of D-loop structures through synthesis-dependent strand annealing, DNA double-strand break repair, ATM pathway and the BRCA1 pathway. It is known to be involved in the homologous strand exchange, a key step in DNA repair through homologous recombination and repair of DNA. It catalyses the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Rad51 is highly expressed in the testis and thymus and less expressed in the small intestine, placenta, colon, pancreas and ovary. Mutations in the RAD51 gene result in breast cancer and Fanconi anemia, a disorder affecting all bone marrow elements. STJ99103 was developed from clone 4H10-G5-H4. It was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Rad51 and does not cross-react with related proteins.
    特异性
    This antibody detects endogenous levels of Rad51 and does not cross-react with related proteins.
    产品特性
    Mouse Monoclonal to Rad51.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Recombinant peptide derived from human Rad51.
    克隆位点
    4H10-G5-H4
    亚型
    IgG2a
    Top Product
    Discover our top product RAD51 Primary Antibody
  • 应用备注
    WB 1:500-2000
    ELISA 1:10000-20000
    说明

    Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    RAD51 (DNA Repair Protein Homolog 1 (RAD51))
    别名
    Rad51 (RAD51 产品)
    别名
    BRCC5 antibody, HRAD51 antibody, HsRad51 antibody, HsT16930 antibody, MRMV2 antibody, RAD51A antibody, RECA antibody, CRAD51 antibody, wu:fb38e12 antibody, zgc:77754 antibody, RGD1563603 antibody, ATRAD51 antibody, F22D1.20 antibody, F22D1_20 antibody, RAS associated with diabetes protein 51 antibody, AV304093 antibody, Rad51a antibody, Reca antibody, brcc5 antibody, rad51 antibody, rad51a antibody, reca antibody, xrad51 antibody, RAD51 recombinase antibody, RAS associated with diabetes protein 51 antibody, RAD51 recombinase L homeolog antibody, RAD51 antibody, rad51 antibody, Rad51 antibody, rad51.L antibody
    分子量
    37kDa
    基因ID
    5888
    UniProt
    Q06609
    途径
    DNA Damage Repair
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