WWP1 抗体 (Internal Region)
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- 抗原 See all WWP1 抗体
- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WWP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Reacts with human WWP1 protein
- 纯化方法
- Purified (protein A)
- 免疫原
- Synthetic peptide derived from internal part of human WWP1 protein
- Top Product
- Discover our top product WWP1 Primary Antibody
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- 应用备注
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
WB(1:200 - 1:2000) - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water.
- 浓度
- 1 mg/mL
- 缓冲液
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 24 months
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- 抗原
- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
- 别名
- NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1 产品)
- 别名
- AIP5 antibody, Tiul1 antibody, hSDRP1 antibody, 8030445B08Rik antibody, SDRP1 antibody, WWP1 antibody, aip5 antibody, tiul1 antibody, hsdrp1 antibody, WW domain containing E3 ubiquitin protein ligase 1 antibody, WWP1 antibody, Wwp1 antibody, wwp1 antibody
- 背景
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF
- UniProt
- Q9H0M0
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