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- 抗原 See all FCAR 抗体
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
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适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCAR antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody A59 recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages.
- 交叉反应 （详细）
- Human, Non-Human Primates
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Ag8.653 myeloma cells
- 克隆位点
- A59
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FCAR Primary Antibody
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anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 22-227) antibody
FCAR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F9D8 unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 51-280) antibodyFCAR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibody (APC)FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 APC
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 131-230) antibodyFCAR 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 1-287) antibodyFCAR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 58-84) antibodyFCAR 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibody (FITC)FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 FITC
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 22-227) antibodyFCAR 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- 别名
- CD89 (FCAR 产品)
- 别名
- CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody
- 背景
- Fc fragment of IgA receptor,CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes, monocytes, macrophages, dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes, stimulators (such as LPS, PMA), TNF alpha, IL1 beta or GM-CSF, and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense.,FcalphaRI, FcAR, CTB-61M7.2
- 基因ID
- 2204
- UniProt
- P24071
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