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FCAR 抗体

FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 unconjugated
产品编号 ABIN4888509
发货至: 中国
  • 抗原 See all FCAR 抗体
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    适用
    • 62
    • 21
    • 9
    • 3
    • 3
    人, Non-Human Primate
    宿主
    • 49
    • 18
    小鼠
    克隆类型
    • 50
    • 16
    • 1
    单克隆
    标记
    • 29
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCAR antibody is un-conjugated
    应用范围
    • 27
    • 23
    • 19
    • 13
    • 13
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody A59 recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Ag8.653 myeloma cells
    克隆位点
    A59
    亚型
    IgG1 kappa
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    Discover our top product FCAR Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    别名
    CD89 (FCAR 产品)
    别名
    CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody
    背景
    Fc fragment of IgA receptor,CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes, monocytes, macrophages, dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes, stimulators (such as LPS, PMA), TNF alpha, IL1 beta or GM-CSF, and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense.,FcalphaRI, FcAR, CTB-61M7.2
    基因ID
    2204
    UniProt
    P24071
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