PNP 抗体 (Middle Region)
-
- 抗原 See all PNP (NP) 抗体
- PNP (NP) (Nucleoside Phosphorylase (NP))
-
抗原表位
- AA 161-189, Middle Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PNP antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Purine nucleoside phosphorylase(PNP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- AMSDAYDRTM RQRALSTWKQ MGEQRELQE
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Purine nucleoside phosphorylase(PNP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: purine nucleoside phosphorylase
Protein Name: Purine nucleoside phosphorylase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PNP (161-189aa AMSDAYDRTMRQRALSTWKQMGEQRELQE), different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NP Primary Antibody
-
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- PNP (NP) (Nucleoside Phosphorylase (NP))
- 别名
- PNP (NP 产品)
- 别名
- NP antibody, PRO1837 antibody, PUNP antibody, Np antibody, AL024301 antibody, AU015798 antibody, Np-1 antibody, Np-2 antibody, Pnp1 antibody, purine nucleoside phosphorylase antibody, purine-nucleoside phosphorylase antibody, PNP antibody, Pnp antibody
- 物质类
- Viral Protein
- 背景
-
The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T-lymphocyte function and neurologic dysfunction.
Synonyms: Inosine phosphorylase | NP | Np1 | Nucleoside phosphorylase | PNP | Pnp1 | PRO1837 | PUNP | P00491 - 基因ID
- 4860
- UniProt
- P00491
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
-