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MGP 抗体 (AA 20-96)

MGP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886666
发货至: 中国
  • 抗原 See all MGP 抗体
    MGP (Matrix Gla Protein (MGP))
    抗原表位
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-96
    适用
    • 22
    • 18
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 33
    • 5
    • 1
    • 1
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 20
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MGP antibody is un-conjugated
    应用范围
    • 28
    • 20
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Matrix Gla protein(MGP) detection. Tested with WB, IHC-P in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Matrix Gla protein(MGP) detection. Tested with WB, IHC-P in Human.
    Gene Name: matrix Gla protein
    Protein Name: Matrix Gla protein
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human MGP recombinant protein (Position: Y20-F96). Human MGP shares 84.4% and 80.5% amino acid (aa) sequence identity with mouse and rat MGP, respectively.
    亚型
    IgG
    Top Product
    Discover our top product MGP Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    MGP (Matrix Gla Protein (MGP))
    别名
    MGP (MGP 产品)
    别名
    MGLAP antibody, NTI antibody, Mglap antibody, mgp-A antibody, MGP antibody, LOC100136434 antibody, mgp antibody, matrix Gla protein antibody, matrix Gla protein L homeolog antibody, MGP antibody, Mgp antibody, mgp.L antibody, mgp antibody
    背景
    Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. In addition, MGP is a 10-kD protein produced and secreted by vascular smooth muscle cells and chondrocytes and significantly accumulated in bone, cartilage, and dentin. It is also expressed at high levels in heart, kidney, and lung and is upregulated by vitamin D in bone cells. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. And this gene is mapped to 12p12.3.

    Synonyms: GIG36 | Matrix Gla protein | MGLAP | MGP | NTI | P08493
    基因ID
    4256
    UniProt
    P08493
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