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CPB2 抗体 (AA 166-388)

Name: CPB2 抗体 (AA 166-388)
SKU: ABIN4886545
Availability: OutOfStock

CPB2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of CPB2 expression in human placenta extract ( Lane 1) and HEPG2 whole cell lysates ( Lane 2). (CPB2 抗体 (AA 166-388))

CPB2 was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- CPB2 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (CPB2 抗体 (AA 166-388))

IHC

2 images

(1 reference)

产品编号 ABIN4886545

发货至: 中国

Datasheet as PDF

抗原 See all CPB2 抗体

CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
抗原表位
15

6

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 166-388
适用
53

23

11

2

1

1

1

1
人
宿主
57

7

4
兔
Compatible Secondaries
克隆类型
62

6
多克隆
标记
31

8

7

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CPB2 antibody is un-conjugated
应用范围
37

20

13

13

13

8

6

4

4

3

2

2

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Carboxypeptidase B2(CPB2) detection. Tested with WB, IHC-P, ELISA in Human.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Carboxypeptidase B2(CPB2) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: carboxypeptidase B2
Protein Name: Carboxypeptidase B2

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human CPB2 recombinant protein (Position: K166-D388). Human CPB2 shares 86.1% and 85.7% amino acid (aa) sequence identity with mouse and rat CPB2, respectively.

亚型

IgG

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CPB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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CPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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CPB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

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CPB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibody
CPB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibody
CPB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) antibody
CPB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 324-373) antibody
CPB2 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 310-410) antibody
CPB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Qin, Zeng, Tian, Deng, Ren, Zheng, Li, Li, Liao, Chen: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).
抗原

CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

别名

CPB2 (CPB2 产品)

别名

CPU antibody, PCPB antibody, TAFI antibody, 1110032P04Rik antibody, 4930405E17Rik antibody, AI255929 antibody, CPR antibody, Cpu antibody, pCPB antibody, zgc:112493 antibody, carboxypeptidase B2 antibody, carboxypeptidase B2 (plasma) antibody, CPB2 antibody, Cpb2 antibody, cpb2 antibody

背景

Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

Synonyms: Carboxypeptidase U | CarboxypeptidaseU | CarboxypeptidaseB2 | Carboxypeptidase B2 | CP B2 | CPB2 | CPB 2 | CPU | PCPB | Procarboxypeptidase B | Procarboxypeptidase R | Procarboxypeptidase U | TAFI | Q96IY4

基因ID

1361

途径

Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis