Cofilin 2 抗体 (C-Term)
-
- 抗原 See all Cofilin 2 (CFL2) 抗体
- Cofilin 2 (CFL2)
-
抗原表位
- AA 121-153, C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Cofilin 2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Cofilin-2(CFL2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKL
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Cofilin-2(CFL2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cofilin 2
Protein Name: Cofilin-2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin 2 (121-153aa KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKL), identical to the related mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product CFL2 Primary Antibody
-
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- Cofilin 2 (CFL2)
- 别名
- CFL2 (CFL2 产品)
- 别名
- NEM7 antibody, CFL2 antibody, zgc:77288 antibody, cf12 antibody, cofilin 2 antibody, cofilin 2 (non-muscle) antibody, cofilin 2 (muscle) antibody, cofilin 2, muscle antibody, cofilin-2 antibody, CFL2 antibody, cfl2 antibody, Cfl2 antibody, cf12 antibody, LOC100359205 antibody
- 背景
-
Cofilin 2 (muscle), also known as CFL2, is a protein which in humans is encoded by the CFL2 gene. It is mapped to 14q12. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. And this protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Synonyms: CFL 2 | CFL2 | CFL-2 | Cofilin 2 muscle | Cofilin | Cofilin muscle | Cofilin2 | Cofilin 2 | Cofilin-2 | NEM 7 | NEM7 | Q9Y281 - 基因ID
- 1073
- UniProt
- Q9Y281
- 途径
- Caspase Cascade in Apoptosis
-