Osteocalcin 抗体 (AA 50-95)
(6 references)-
- 抗原 See all Osteocalcin (BGLAP) 抗体
- Osteocalcin (BGLAP)
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抗原表位
- AA 50-95
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Osteocalcin antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Mouse.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Mouse.
Gene Name: bone gamma-carboxyglutamate (gla) protein
Protein Name: Osteocalcin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived mouse Osteocalcin recombinant protein (Position: Y50-I95). Mouse Osteocalcin shares 69% and 68.9% amino acid (aa) sequence identity with human and rat Osteocalcin, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product BGLAP Primary Antibody
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anti-Osteocalcin (BGLAP) (AA 14-95) antibody
BGLAP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 21-100) antibodyBGLAP 适用: 人, 大鼠, 小鼠, 犬 ELISA, WB, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 52-100) antibodyBGLAP 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Osteocalcin (BGLAP) (AA 1-100) antibodyBGLAP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 21-80) antibodyBGLAP 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC (p), IHC (fro), FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 52-100) antibodyBGLAP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) antibodyBGLAP 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 2-32) antibodyBGLAP 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 11-98) antibodyBGLAP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Osteocalcin (BGLAP) (AA 21-99) antibodyBGLAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein-2 on bone induction." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4483-4492, (2018) (PubMed).
: "Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181133, (2017) (PubMed).
: "Intramuscular injection of bone marrow mononuclear cells contributes to bone repair following midpalatal expansion in rats." in: Molecular medicine reports, Vol. 13, Issue 1, pp. 681-8, (2016) (PubMed).
: "Effects of Naringin on Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells In Vitro and In Vivo." in: Stem cells international, Vol. 2015, pp. 758706, (2015) (PubMed).
: "The osteogenic potential of mesoporous bioglasses/silk and non-mesoporous bioglasses/silk scaffolds in ovariectomized rats: in vitro and in vivo evaluation." in: PLoS ONE, Vol. 8, Issue 11, pp. e81014, (2014) (PubMed).
: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).
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: "Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein-2 on bone induction." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4483-4492, (2018) (PubMed).
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- 抗原
- Osteocalcin (BGLAP)
- 别名
- BGLAP (BGLAP 产品)
- 别名
- BGP antibody, OC antibody, OCN antibody, Bglap1 antibody, Bglap2 antibody, OG1 antibody, mOC-A antibody, Bgp antibody, Bgpr antibody, Bgpra antibody, bgp antibody, LOC792433 antibody, ocn antibody, GLA antibody, BGLAP antibody, PMF1 antibody, bone gamma-carboxyglutamate protein antibody, bone gamma carboxyglutamate protein antibody, bone gamma-carboxyglutamate protein S homeolog antibody, bone gamma-carboxyglutamate (gla) protein antibody, osteocalcin antibody, polyamine-modulated factor 1 antibody, BGLAP antibody, Bglap antibody, bglap.S antibody, bglap antibody, ocn antibody, LOC100529177 antibody, LOC100146589 antibody
- 背景
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Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.
Synonyms: BGLAP | Bone Gla protein | ocn | OSTCN HUMAN | Osteocalcin | P86546 - 基因ID
- 12096
- UniProt
- P86546
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