AKR1B1 抗体 (AA 228-316)
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- 抗原 See all AKR1B1 抗体
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
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抗原表位
- AA 228-316
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKR1B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Aldose reductase(AKR1B1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Aldose reductase(AKR1B1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: aldo-keto reductase family 1 member B
Protein Name: Aldose reductase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human AKR1B1 recombinant protein (Position: L228-F316). Human AKR1B1 shares 87.5% amino acid (aa) sequence identity with both mouse and rat AKR1B1.
- 亚型
- IgG
- Top Product
- Discover our top product AKR1B1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
- 别名
- AKR1B1 (AKR1B1 产品)
- 别名
- ADR antibody, ALDR1 antibody, ALR2 antibody, AR antibody, ALDRED antibody, ALR-P-I antibody, Akr1b3 antibody, Akr1b4 antibody, Aldr1 antibody, Alr antibody, RATALDRED antibody, akr1b7 antibody, zgc:86611 antibody, aldo-keto reductase family 1 member B antibody, aldo-keto reductase family 1, member B1 (aldose reductase) antibody, aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog antibody, AKR1B1 antibody, Akr1b1 antibody, akr1b1.S antibody, akr1b1 antibody
- 背景
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Aldo-keto reductase family 1, member B1 (aldose reductase), also known as AR, is an enzyme that in humans is encoded by the AKR1B1 gene. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number ofaldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
Synonyms: ADR | AKR1B 1 | Akr1b1 | Aldehyde reductase 1 | Aldehyde reductase | Aldose reductase | aldr 1 | aldr1 | ALR2 | AR | P15121 - 基因ID
- 231
- UniProt
- P15121
- 途径
- Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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