MLL4 抗体 (C-Term)
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- 抗原 See all MLL4 抗体
- MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This MLL4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to MLL4.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence CNCGAKRCRRFLN, from the C Terminus of the protein sequence according to NP_055542.
- Top Product
- Discover our top product MLL4 Primary Antibody
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anti-Histone-Lysine N-Methyltransferase MLL4 (MLL4) (AA 813-904) antibody
MLL4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Histone-Lysine N-Methyltransferase MLL4 (MLL4) (N-Term) antibodyMLL4 适用: 人, 小鼠, 大鼠, 兔, Cow, Saccharomyces cerevisiae, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Histone-Lysine N-Methyltransferase MLL4 (MLL4) antibodyMLL4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/128000. Western blot: Preliminary experiments gave no signal but low background in Human Heartlysates at up to 1 μg/mL. However this used our routine western blotting protocol which wewould not expect to reliably detect proteins as large as the predicted size of approx.312KDa according to NP_055542. Immunohistochemistry on paraffin sections: Human Testis shows cytoplasm staining ofspermatids. Recommended concentration: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))
- 别名
- MLL4 (MLL4 产品)
- 别名
- HRX2 antibody, MLL1B antibody, MLL2 antibody, MLL4 antibody, TRX2 antibody, WBP7 antibody, 2610014H22Rik antibody, Mll2 antibody, Wbp7 antibody, mKIAA0304 antibody, ALR antibody, BC032281 antibody, BC058659 antibody, C430014K11Rik antibody, KMT2B antibody, Mll4 antibody, RGD1308331 antibody, lysine methyltransferase 2B antibody, lysine (K)-specific methyltransferase 2B antibody, lysine (K)-specific methyltransferase 2D antibody, KMT2B antibody, Kmt2b antibody, Kmt2d antibody
- 背景
- KMT2D / MLL4 contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This protein is ubiquitously expressed in adult tissues where it possibly acts as a transcriptional regulatory factor. It is also expressed in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced gene transcripts encoding distinct isoforms have been reported, however, the full length nature of the shorter transcript is not known.Synonyms: HRX2, Histone-lysine N-methyltransferase MLL4, KIAA0304, KMT2D, Lysine N-methyltransferase 2D, MLL2, Myeloid/lymphoid or mixed-lineage leukemia protein 4, TRX2, Trithorax homolog 2, WBP7, WW domain-binding protein 7
- 基因ID
- 9757
- NCBI登录号
- NP_055542
- UniProt
- Q9UMN6
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect
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