Gestrinone 抗体
EIA
宿主: 绵羊
Polyclonal
unconjugated
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- 抗原
- Gestrinone
- 适用
- 请咨询
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宿主
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绵羊
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Enzyme Immunoassay (EIA)
- 纯化方法
- Ig Fraction
- 免疫原
- Gestrinone-BTG
- 亚型
- IgG
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- 应用备注
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ELISA: 0.039 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 10.20 mg/mL (U.V.abs at 280nm)
- 缓冲液
- 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at-20 °C.
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- 抗原
- Gestrinone
- 物质类
- Hormone
- 背景
- Endometriosis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10 % of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosis.(1) It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone (LH) and follicle-stimulating hormone (FSH), thus reducing estrogen synthesis.(1) It also binds to androgen (AR), progesterone (PR), and estrogen (ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin.(2) Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively.(3) These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.(3)Synonyms: Dimetriose, Dimetrose, Ethylnorgestrienone, Gestrigone, Gestrinonum, Nemestran, Tridomose
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