COR
IHC, WB, ELISA, IC
宿主: 兔
Polyclonal
unconjugated
应用备注
ELISA: 1.25 μg/mL, 10 ng/mL cortisone produces 73 % inhibition in a competitive ELISA,employing cortisone polyclonal antibody. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
状态
Liquid
浓度
7.2mg/mL (U.V.abs at 280nm)
缓冲液
20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Cortisone is a hormone. Chemically it is a corticosteroid with formula C21H28O5 and IUPAC name 17-hydroxy-11-dehydrocorticosterone. It is closely related to corticosterone. Cortisone and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response. Cortisone is the inactive precursor molecule of the active hormone cortisol. It is activated through hydroxylation of the 11-keto-group by an enzyme called 11-beta-steroid dehydrogenase. The active form cortisol is thus sometimes referred to as hydrocortisone. Cortisone is sometimes used as a drug to treat a variety of ailments.Synonyms: 11, 17alpha, 17alpha-Hydroxy-11-dehydrocorticosterone, 20-trione, 21-Dihydroxy-4-pregnene-3, 21-diol-3, 4-Pregnene-17alpha