Keratin 5/14 抗体 (C-Term)
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- 抗原 See all Keratin 5/14 (KRT5/14) products
- Keratin 5/14 (KRT5/14)
- 抗原表位
- C-Term
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Keratin 5/14 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58kD protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified epithelial cells from simple epithelial cells. Species cross-reactivity: This antibody is reactive against human.
- 纯化方法
- Purified
- 免疫原
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Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminal region of the human cytokeratin 5 molecule. LLLLL: Synthetic peptide of the extreme c-terminal of human keratin-14.
Type of Immunogen: Synthetic peptide - 亚型
- IgG1, IgG3
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- 应用备注
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Approved: ICC, IF, IHC, IHC-Fr
Usage: Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (Fr) and Immunocytochemistry. Positive control: Skin. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.2, 0.08 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Do not freeze. Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing will result in a substantial loss of activity.
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- 抗原
- Keratin 5/14 (KRT5/14)
- 别名
- Cytokeratin 5+14 (KRT5/14 产品)
- 背景
- This antibody detects: Cytokeratin 5+14
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