Insulin C-Peptide 抗体
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- 抗原 See all Insulin C-Peptide products
- Insulin C-Peptide
- 适用
- 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Insulin C-Peptide antibody is un-conjugated
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应用范围
- ELISA
- 特异性
- Recognizes rat C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes rat and mouse C-peptide I and rat C-peptide II with equal affinity. Reacts weakly with mouse C-peptide II. It does not recognize rat proinsulin. May be used as a capture antibody in ELISA assays for rat or mouse C-peptides I or II.
- 纯化方法
- Affinity purified
- 免疫原
- Fragments of rat C-peptide conjugated to a carrier protein.
- 克隆位点
- CC34
- 亚型
- IgG1
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- 应用备注
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Approved: ELISA, SwELISA
Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA ?to detect rat C-peptide I together with LS-C58408 as a detection reagent. These sandwich ELISA combinations are not suitable for the detection of mouse C-peptide I or II. - 说明
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Target Species of Antibody: Rat
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Short term: -20°C
Long term: -20°C.
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- 抗原
- Insulin C-Peptide
- Abstract
- Insulin C-Peptide 产品
- 别名
- IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, insulin antibody, INS antibody
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