EBV LMP2A 抗体
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- 抗原 See all EBV LMP2A products
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- 适用
- Epstein-Barr Virus (EBV)
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宿主
- 大鼠
- 克隆类型
- 单克隆
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标记
- This EBV LMP2A antibody is un-conjugated
- 应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.
- 纯化方法
- Affinity purified
- 免疫原
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Bacterial TrpE-LMP2A fusion protein.
Type of Immunogen: Fusion protein - 克隆位点
- 15F9
- 亚型
- IgG1
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- 应用备注
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Approved: IHC, IHC-P, WB (1:100 - 1:1000)
Usage: Immunohistology: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. - 说明
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Target Species of Antibody: Epstein-Barr Virus
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Short term: -20°C
Long term: -20°C.
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- 抗原
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- 别名
- EBV LMP2A (EBV LMP2A 产品)
- 别名
- - antibody, LMP2A antibody
- 物质类
- Viral Protein
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