HLA-E 抗体
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- 抗原 See all HLA-E 抗体
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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适用
- 人, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-E antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 品牌
- IHC-plus™
- 特异性
- Recognized native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7
- 纯化方法
- Protein A purified
- 免疫原
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Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.
Type of Immunogen: Synthetic peptide - 克隆位点
- MEM-E-06
- 亚型
- IgG1
- Top Product
- Discover our top product HLA-E Primary Antibody
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- 应用备注
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Approved: Flo, IHC, IHC-P (10 μg/mL), IP
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Tris buffered saline (TBS), 15 mM sodium azide, approx, pH 8.0. Sourced in Ascites.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- avoid freeze thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- 抗原
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
- 别名
- HLA-E (HLA-E 产品)
- 别名
- EA1.2 antibody, EA2.1 antibody, HLA-6.2 antibody, MHC antibody, QA1 antibody, major histocompatibility complex, class I, E antibody, HLA-E antibody, PATR-E antibody
- UniProt
- P13747
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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