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PRR7 抗体 (C-Term, Intracellular)

PRR7 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 小鼠 Monoclonal TRAP3-10 unconjugated
产品编号 ABIN457438
发货至: 中国
  • 抗原 See all PRR7 抗体
    PRR7 (Proline Rich 7 (Synaptic) (PRR7))
    抗原表位
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    C-Term, Intracellular
    适用
    • 20
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 18
    • 2
    小鼠
    克隆类型
    • 18
    • 2
    单克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    This PRR7 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    特异性
    The mouse monoclonal antibody TRAP3/10 recognizes an epitope located in the C-terminal part of the intracellular domain of PRR7/TRAP3 (amino acids 126-253 of human PRR7 / TRAP3), a 28 kDa proline-rich membrane protein presumably associated with NMDA receptor complex.
    交叉反应 (详细)
    Human, Mouse, Rat
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Recombinant C-terminal half of the intracellular domain of human PRR7/TRAP3 (amino acids 126-253)
    克隆位点
    TRAP3-10
    亚型
    IgG2a
  • 应用备注
    Immunocytochemistry: Recommended dilution: 10 μg/mL, cell culture fixed with 4 % paraformaldehyde, permeabilized with 0.1 % Triton-X100.
    Western blotting: Recommended dilution: 1 μg/mL, positive control: murine brain lysate (red. Laemmli buffer).
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Hrdinka, Dráber, Stepánek, Ormsby, Otáhal, Angelisová, Brdicka, Paces, Horejsí, Drbal: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).

  • 抗原
    PRR7 (Proline Rich 7 (Synaptic) (PRR7))
    别名
    PRR7 / TRAP3 (PRR7 产品)
    别名
    PRR7 antibody, XM_484263 antibody, proline rich 7, synaptic antibody, proline rich 7 (synaptic) antibody, proline rich 7 (synaptic) L homeolog antibody, PRR7 antibody, prr7 antibody, prr7.L antibody, Prr7 antibody
    背景
    Proline rich 7, synaptic,PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.,TRAP3
    基因ID
    80758
    UniProt
    Q8TB68
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