L-Selectin 抗体
(9 references)-
- 抗原 See all L-Selectin (SELL) 抗体
- L-Selectin (SELL) (Selectin L (SELL))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This L-Selectin antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- The rat monoclonal antibody MEL-14 reacts with an extracellular epitope of murine CD62L (L-selectin), a 75 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.
- 交叉反应 （详细）
- Mouse
- 纯化方法
- Purified by protein-G affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- 免疫原
- C3H/eb mouse B cell lymphoma 38C-13
- 克隆位点
- Mel-14
- 亚型
- IgG2a
- Top Product
- Discover our top product SELL Primary Antibody
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anti-Selectin L (SELL) (AA 301-372) antibody
SELL 适用: 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Selectin L (SELL) (AA 1-100) antibodySELL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin L (SELL) antibody (APC)SELL 适用: 人 FACS 宿主: 小鼠 Monoclonal LT-TD180 APC
anti-Selectin L (SELL) (AA 83-186) antibodySELL 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8C8B7 unconjugated
anti-Selectin L (SELL) (AA 109-346) antibodySELL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin L (SELL) antibodySELL 适用: 人, Cow FACS, IP, ICC 宿主: 小鼠 Monoclonal IVA94 unconjugated
anti-Selectin L (SELL) antibody (FITC)SELL 适用: 人 FACS 宿主: 小鼠 Monoclonal DREG56 FITC
anti-Selectin L (SELL) antibodySELL 适用: 小鼠 FACS, IP, IHC (fro), ICC, IHC (p) 宿主: 大鼠 Monoclonal Mel-14 unconjugated
anti-Selectin L (SELL) antibody (FITC)SELL 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal Mel-14 FITC
anti-Selectin L (SELL) antibodySELL 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal DREG56 unconjugated
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- 应用备注
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Functional application: Blocking of cell adhesion.
Flow cytometry: Recommended dilution: 1-4 μg/mL. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Critical but divergent roles for CD62L and CD44 in directing blood monocyte trafficking in vivo during inflammation." in: Blood, Vol. 112, Issue 4, pp. 1166-74, (2008) (PubMed).
: "The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice." in: Diabetes, Vol. 56, Issue 5, pp. 1395-402, (2007) (PubMed).
: "CD62L (L-selectin) down-regulation does not affect memory T cell distribution but failure to shed compromises anti-viral immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 1, pp. 198-206, (2007) (PubMed).
: "Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease." in: Blood, Vol. 103, Issue 4, pp. 1534-41, (2004) (PubMed).
: "Bryostatin 1/ionomycin (B/I) ex vivo stimulation preferentially activates L-selectinlow tumor-sensitized lymphocytes." in: International immunology, Vol. 16, Issue 9, pp. 1283-94, (2004) (PubMed).
: "L-selectin is not required for T cell-mediated autoimmune diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 6, pp. 2659-66, (2002) (PubMed).
: "Interleukin-2 and loss of immunity in experimental Mycobacterium avium infection." in: Infection and immunity, Vol. 70, Issue 1, pp. 27-35, (2001) (PubMed).
: "The proportion of CD45RA(+)CD62L(+) (quiescent-phenotype) T cells within the CD8(+) subset increases in advanced weight loss in the protein- or energy-deficient weanling mouse." in: The Journal of nutrition, Vol. 131, Issue 12, pp. 3266-9, (2001) (PubMed).
: "Hierarchal utilization of different T-cell receptor Vbeta gene segments in the CD8(+)-T-cell response to an immunodominant Moloney leukemia virus-encoded epitope in vivo." in: Journal of virology, Vol. 73, Issue 11, pp. 9161-9, (1999) (PubMed).
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: "Critical but divergent roles for CD62L and CD44 in directing blood monocyte trafficking in vivo during inflammation." in: Blood, Vol. 112, Issue 4, pp. 1166-74, (2008) (PubMed).
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- 抗原
- L-Selectin (SELL) (Selectin L (SELL))
- 别名
- CD62L / L-Selectin (SELL 产品)
- 别名
- CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
- 背景
- Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, Lsel, Sell, Lam1, Lecam, Leu8, Lnhr, Lyam1, Plnhr
- 基因ID
- 20343
- UniProt
- Q3TCF3
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