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TYMS 抗体 (N-Term)

TYMS 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal AT1S5 unconjugated
产品编号 ABIN452662
发货至: 中国
  • 抗原 See all TYMS 抗体
    TYMS (Thymidylate Synthetase (TYMS))
    抗原表位
    • 15
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-313, N-Term
    适用
    • 97
    • 29
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 55
    • 41
    • 1
    小鼠
    克隆类型
    • 50
    • 47
    单克隆
    标记
    • 45
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TYMS antibody is un-conjugated
    应用范围
    • 50
    • 41
    • 34
    • 22
    • 19
    • 19
    • 18
    • 17
    • 14
    • 13
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    The antibody recognizes human TYMS. Other species not tested.
    产品特性
    Synonyms: TYMS, TSase, OK/SW-cl.29
    纯化方法
    Protein-G affinity chromatography
    免疫原
    Recombinant TYMS (1-313 aa) purified from E. coli
    克隆位点
    AT1S5
    亚型
    IgG2b
    Top Product
    Discover our top product TYMS Primary Antibody
  • 应用备注
    ELISA. Western blot (1: 500 - 1: 1,000). Immunofluorescence (1: 500 - 1: 1,000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, containing 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    TYMS (Thymidylate Synthetase (TYMS))
    别名
    Thymidylate Synthase (TS) (TYMS 产品)
    别名
    FN1 antibody, ECK2823 antibody, JW2795 antibody, ts antibody, Ts antibody, HST422 antibody, TMS antibody, TS antibody, thymidylate synthetase antibody, contains intron in T4 phage antibody, ThyE antibody, thymidylate synthase antibody, thymidylate synthetase L homeolog antibody, TYMS antibody, thyA antibody, td antibody, thyE antibody, DDA3937_RS04960 antibody, tyms.L antibody, XBJ1_RS15770 antibody, EAMY_RS20680 antibody, Tyms antibody
    物质类
    Viral Protein
    背景
    The methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dMTP) is an essential step for the formation of thymine nucleotides. This process is catalyzed by thymidylate synthase (TS or TYMS). TYMS is an intracellular enzyme that provides the sole de novo source of thymidylate in activity highest proliferating cells. Being the exclusive source of dTMP, TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head and neck. TS expression may be useful in predicting overall patient survival, but the prognostic value of TS expression continues to be a subject of investigation for different types of cancers.Synonyms: OK/SW-cl.29, TSase, TYMS
    基因ID
    54583
    UniProt
    P04818
    途径
    Mitotic G1-G1/S Phases
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