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CD41, CD61 抗体

适用: 人 EIA, WB 宿主: 小鼠 Monoclonal 291 unconjugated
产品编号 ABIN452604
发货至: 中国
  • 抗原 See all CD41, CD61 抗体
    CD41, CD61 (CD41,CD61)
    适用
    • 11
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    小鼠
    克隆类型
    • 19
    单克隆
    标记
    • 9
    • 4
    • 4
    • 1
    • 1
    This CD41, CD61 antibody is un-conjugated
    应用范围
    • 16
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: Platelet Membrane GPIIb-IIIa Complex, CD41b, CD61, GP3A, GPIIIa, GPIIIb, GTA, HPA3,Integrin alpha 2b, Integrin beta 3
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    10e9 Human platelets suspension. The supernatant fluid from positive clones was screened by ELISA coated with washedplatelets.
    克隆位点
    291
    亚型
    IgG2b
    Top Product
    Discover our top product CD41, CD61 Primary Antibody
  • 应用备注
    This GPIIb/IIIa antibody is Suitable for use in ELISA and Western Blot. Use of this Monoclonal antibody at a concentration of 10-20 μg/mL (culture supernatants)will allow visualization of NP 40 solubilized human normal platelets. The titer of purified ascites was determined by ELISA coated with 100 μL of 1x10e8 washedplatelets.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
    缓冲液
    0.01 M PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD41, CD61 (CD41,CD61)
    Abstract
    CD41, CD61 产品
    背景
    The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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