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HCV NS4 抗体

This anti-HCV NS4 antibody is a 小鼠 单克隆 antibody detecting HCV NS4 in EIA. Suitable for 人.
产品编号 ABIN452532
发货至: 中国

Quick Overview for HCV NS4 抗体 (ABIN452532)

抗原

HCV NS4 (Hepatitis C Virus NS4 (HCV NS4))

适用

  • 19
  • 3

宿主

  • 20
  • 2
小鼠

克隆类型

  • 20
  • 2
单克隆

标记

  • 20
  • 2
This HCV NS4 antibody is un-conjugated

应用范围

  • 19
  • 13
  • 9
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Enzyme Immunoassay (EIA)

克隆位点

202
  • 交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: Hepatitis C Virus, Non-structural protein NS4A, NS4B

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Purified Recombinant Chimeric HCV Polyprotein (555 a. a. )

    亚型

    IgA
  • 应用备注

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

    缓冲液

    0.01 M PBS, pH 7.0 without preservatives.

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    HCV NS4 (Hepatitis C Virus NS4 (HCV NS4))

    别名

    HCV NS4

    物质类

    Viral Protein

    背景

    NS4 A/B are two of the seven nonstructural (NS) proteins making up the HCV polyprotein. The NS proteins recruit the viral genome into an RNA replication complex, which is associated with rearranged cytoplasmic membranes. NS4A acts as a cofactor with the NS3 serine protease and stabilizes its folding. The NS3-NS4A complex is essential for the activation of the latter and allows membrane anchorage of NS3. HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. HCV is responsible for a large proportion of worldwide chronic viral hepatitides. Most of these infections develop into chronic hepatitis, which often progresses to liver cirrhosis and hepatocellular carcinoma. At present, (unlike hepatitis A and B), there is no vaccine to prevent hepatitis C infection. The hepatitis C virus (HCV) nonstructural protein 4B (NS4B) is a relatively hydrophobic 27- kDa protein. The 4A protein has a molecular weight of 6 kDa.Synonyms: Hepatitis C Virus, NS4B, Non-structural protein NS4A
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