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HBSAg 抗体

HBsAg 适用: Hepatitis B Virus (HBV) IHC (p) 宿主: 小鼠 Monoclonal P3G9A8 unconjugated
产品编号 ABIN452186
发货至: 中国
  • 抗原 See all HBSAg (HBsAg) 抗体
    HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))
    适用
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    Hepatitis B Virus (HBV)
    宿主
    • 58
    • 36
    • 26
    • 2
    小鼠
    克隆类型
    • 58
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    单克隆
    标记
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    This HBSAg antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Synonyms: HBV Large envelope protein, L glycoprotein, Large S protein, Large surface protein, HBVMajor surface antigen
    免疫原
    Purified Hepatitis B surface antigen.
    克隆位点
    P3G9A8
    亚型
    IgG1
    Top Product
    Discover our top product HBsAg Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections: 1/10-1/25 (No protease pre-treatment). Blocking of endogenous Peroxidase with 1 % Peroxide in Methanol is recommended. Positive Control: HBV infected liver. Incubation Time: 60 min at RT or 2-8 °C overnight.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Stabilized Phosphate buffer, pH 7.3 containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))
    别名
    Hepatitis B Surface Antigen / HBsAg (HBsAg 产品)
    物质类
    Viral Protein
    背景
    Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.Synonyms: HBV surface antigen, Hepatitis B Virus
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