p53 抗体 (AA 20-31)
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- 抗原 See all p53 (TP53) 抗体
- p53 (TP53) (Tumor Protein P53 (TP53))
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抗原表位
- AA 20-31
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This p53 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 特异性
- P53
- 交叉反应
- 人
- 纯化方法
- Protein A affinity column
- 免疫原
- Recombinant human p53 (transcription domain within the NH2 terminus)
- 克隆位点
- Bp53-11
- 亚型
- IgG2a
- Top Product
- Discover our top product TP53 Primary Antibody
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- 应用备注
- IHC: 1:500, when using the APAAP method
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- reconstitue with 1 mL deionized water
- 浓度
- 0.025 mg/mL
- 缓冲液
- PBS, pH 7.4, 0.09 % Sodium azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 2-8°C, extended storage at -20°C, avoid repeated freeze-thaw cycles
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Expression of cadherins, p53, and BCL2 in small cell carcinomas of the cervix: potential tumor suppressor role for N-cadherin." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 13, Issue 2, pp. 240-3, (2003) (PubMed).
: "Precancerous foci in pleomorphic adenoma of the salivary gland: recognition of focal carcinoma and atypical tumor cells by P53 immunohistochemistry." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 31, Issue 10, pp. 590-7, (2002) (PubMed).
: "Overexpression of p53 in tumor-distant epithelia of head and neck cancer patients is associated with an increased incidence of second primary carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 7, Issue 2, pp. 290-6, (2001) (PubMed).
: "Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control." in: Cancer research, Vol. 58, Issue 1, pp. 5-13, (1998) (PubMed).
: "Mapping of linear epitopes recognized by monoclonal antibodies with gene-fragment phage display libraries." in: Molecular & general genetics : MGG, Vol. 249, Issue 4, pp. 425-31, (1996) (PubMed).
: "Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insights into antibody-peptide interactions." in: Journal of molecular biology, Vol. 248, Issue 1, pp. 58-78, (1995) (PubMed).
: "Problems with p53 immunohistochemical staining: the effect of fixation and variation in the methods of evaluation." in: British journal of cancer, Vol. 69, Issue 1, pp. 26-31, (1994) (PubMed).
: "Immunohistochemical analysis of the p53 oncoprotein on paraffin sections using a series of novel monoclonal antibodies." in: The Journal of pathology, Vol. 169, Issue 1, pp. 27-34, (1993) (PubMed).
: "Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro." in: International journal of cancer, Vol. 46, Issue 5, pp. 839-44, (1990) (PubMed).
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Expression of cadherins, p53, and BCL2 in small cell carcinomas of the cervix: potential tumor suppressor role for N-cadherin." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 13, Issue 2, pp. 240-3, (2003) (PubMed).
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- 抗原
- p53 (TP53) (Tumor Protein P53 (TP53))
- 别名
- P53 (TP53 产品)
- 别名
- BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
- 背景
- Excellent marker for wild-type and mutant forms of human p53 antigen. The antibody stains positively approx. 60 % of investigated carcinoma of lung, breast, colon, stomach, esophagus, pancreas, urinary bladder and testis, head and neck tumors, T-cell Leuk
- 基因ID
- 7157
- UniProt
- P04637
- 途径
- p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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