The antibody detects endogenous level of Synaptotagmin only when phosphorylated at Serine 309.
交叉反应 (详细)
Species reactivity (tested):Human, Mouse, Rat.
纯化方法
Affinity Chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
免疫原
Peptide sequence around phosphorylation site of Serine 309 (G-L-S(p)-D-P) derived from Human.
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65