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PTENP1 抗体 (N-Term)

PTENP1 适用: 人, 小鼠, 大鼠, 斑马鱼, Chimpanzee, 犬, Green Pufferfish, Macaque WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401437
发货至: 中国
  • 抗原 See all PTENP1 products
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 斑马鱼, Chimpanzee, 犬, Green Pufferfish, Macaque
    宿主
    • 2
    • 2
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This PTENP1 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine, Macaque, Chimpanzee, Opossum, Zebrafish, Green pufferfish, Platypus.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Purified peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein
    亚型
    IgG
  • 应用备注
    ELISA: 1/160,000. Western Blot: 1/500 to 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.73 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    别名
    PTENP1 (PTENP1 产品)
    别名
    PTEN-rs antibody, PTEN2 antibody, PTENpg1 antibody, PTH2 antibody, psiPTEN antibody, phosphatase and tensin homolog pseudogene 1 antibody, PTENP1 antibody
    背景
    This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.Synonyms: PTEN-rs, PTEN2, PTH2, Phosphatase and tensin homolog 2, Phosphatase and tensin homolog pseudogene 1, psiPTEN
    基因ID
    9606
    UniProt
    O43460
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