LIM Domain Kinase 1 抗体 (AA 630-647)
-
- 抗原 See all LIM Domain Kinase 1 (LIMK1) 抗体
- LIM Domain Kinase 1 (LIMK1)
-
抗原表位
- AA 630-647
-
适用
- 人, 小鼠, 大鼠, Chimpanzee, Orang-Utan
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This LIM Domain Kinase 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to LIM kinase protein.
- 交叉反应 (详细)
-
Species reactivity (expected):Chimpanzee, Orangutan, Mouse, Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Purified
- 免疫原
- Synthetic peptide corresponding aa 630-647 of human LIM kinase protein
- 亚型
- IgG
- Top Product
- Discover our top product LIMK1 Primary Antibody
-
-
- 应用备注
-
ELISA: 1/8000 - 1/36000. Western Blot: 1/500 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
-
- 抗原
- LIM Domain Kinase 1 (LIMK1)
- 别名
- LIMK1 (LIMK1 产品)
- 别名
- limk1 antibody, xlimk1 antibody, GB16654 antibody, LIMK1 antibody, LIMK antibody, LIMK-1 antibody, LIM domain kinase 1 antibody, LIM domain kinase 1a antibody, LIM domain kinase 1 L homeolog antibody, LIM-domain containing, protein kinase antibody, LIMK1 antibody, limk1a antibody, limk1 antibody, CpipJ_CPIJ000717 antibody, LOC413152 antibody, Limk1 antibody, limk1.L antibody
- 背景
- LIM Kinase is also known as LIM-domain containing protein kinase, LIMK-1 and LIMK. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified. LIM kinase has a cytoplamic localization.Synonyms: EC=2.7.11.1, LIM domain kinase 1, LIMK, LIMK-1
- 基因ID
- 3984
- NCBI登录号
- NP_001191355
- UniProt
- P53667
- 途径
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
-