USP7 抗体 (N-Term)
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- 抗原 See all USP7 抗体
- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, Chimpanzee
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This affinity purified antibody is directed against HAUSP protein.
- 交叉反应 （详细）
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Species reactivity (expected):Rat, Mouse, Chimpanzee, Bovine and Dog (100 %).Chicken (92 %, 11/12).Zebrafish (83 %, 10/12).
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide corresponding to amino acids near the amino terminus of Human HAUSP protein
- 亚型
- IgG
- Top Product
- Discover our top product USP7 Primary Antibody
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anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 54-507) antibody
USP7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) antibodyUSP7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 7F10 unconjugated Recombinant Antibody
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 206-1102) antibodyUSP7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 206-1102) antibodyUSP7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) antibodyUSP7 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (Internal Region) antibodyUSP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 1050-1100) antibodyUSP7 适用: 人, 小鼠, 大鼠, 犬, 马, 小鸡, Macaque WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 258-483) antibodyUSP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 302-394), (C-Term) antibodyUSP7 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (AA 30-80) antibodyUSP7 适用: 人, 小鼠, 大鼠, 犬, 马, 小鸡, Macaque WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/15,000-1/60,000. Western blot: 1/500-1/2,000 (Expect a band approximately 130 kDa in size correspondingto HAUSP protein in the appropriate cell lysate or extract).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.98 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or for longer (in aliquots) at-20 °C or below.
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- 抗原
- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
- 别名
- USP7 / HAUSP (USP7 产品)
- 背景
- HAUSP (also known as deubiquitinating enzyme 7, herpes virus associated ubiquitin specific protease, TEF1, ubiquitin carboxyl terminal hydrolase 7, ubiquitin specific protease 7, ubiquitin thiolesterase 7, and USP7) is a novel p53 interacting protein. HAUSP was identified by mass spectrometry of affinity purified p53 associated factors by Li et al. HAUSP strongly stabilizes p53, even in the presence of excess MDM2, and also induces p53- dependent cell growth repression and apoptosis. HAUSP has an intrinsic enzymatic activity that specifically deubiquitinates p53 both in vivo and in vitro. Expression of a catalytically inactive point mutation of HAUSP in cells increased the levels of p53 ubiquitination and also destabilized p53. Li et al concluded that their findings revealed an important mechanism by which p53 can be stabilized by direct de-ubiquitination and also implied that HAUSP may function as a tumor suppressor in vivo through the stabilization of p53.Synonyms: Deubiquitinating enzyme 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin carboxyl-terminal hydrolase 7, Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7
- 基因ID
- 7874
- NCBI登录号
- NP_003461
- UniProt
- Q93009
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