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USP18 抗体 (AA 40-49)

USP18 适用: 人, Chimpanzee, Orang-Utan WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401252
发货至: 中国
  • 抗原 See all USP18 抗体
    USP18 (Ubiquitin Specific Peptidase 18 (USP18))
    抗原表位
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    AA 40-49
    适用
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Chimpanzee, Orang-Utan
    宿主
    • 19
    • 3
    克隆类型
    • 22
    多克隆
    标记
    • 18
    • 2
    • 1
    • 1
    This USP18 antibody is un-conjugated
    应用范围
    • 18
    • 10
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against human UBP43 protein.
    交叉反应 (详细)
    Species reactivity (expected):A BLAST analysis was used to suggest reactivity with this protein from chimpanzee and orangutan based on 100 % homology for the immunogen sequence.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    Synthetic peptide corresponding aa 40-49 of human UBP43 protein
    亚型
    IgG
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  • 应用备注
    ELISA: 1: 10,000 - 1: 50,000. Western blot: 1: 500 - 1: 2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.9 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or for longer (in aliquots) at -20 °C or below.
  • 抗原
    USP18 (Ubiquitin Specific Peptidase 18 (USP18))
    别名
    USP18 (USP18 产品)
    背景
    UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.Synonyms: 43 kDa ISG15-specific protease, ISG15-specific-processing protease, ISG43, Ubl carboxyl-terminal hydrolase 18, Ubl thioesterase 18
    基因ID
    11274
    NCBI登录号
    NP_059110
    UniProt
    Q9UMW8
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