CD28 抗体
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- 抗原 See all CD28 抗体
- CD28
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适用
- 人, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD28 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- The antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
- 产品特性
- Synonyms: TP44, T-cell-specific surface glycoprotein CD28
- 纯化方法
- Affinity Chromatography on Protein A
- 过滤
- 0.2 μm filtered
- 免疫原
- DC28. 1. 3. 3 hybridoma cells
- 克隆位点
- CD28-2
- 亚型
- IgG1
- Top Product
- Discover our top product CD28 Primary Antibody
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- 应用备注
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Flow Cytometry. Immunoprecipitation. Western blot. Immunohistochemistry on frozen sections. Immunoflourescence. Functional Application. T cell costimulation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Azide free Phosphate Buffered Saline (PBS), pH ~7.4, 0.2 μm filter sterilization. Endotoxin level is less than 10 EU/mg of the protein, as determined by the LAL test.
- 储存液
- Azide free
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CD28
- 别名
- CD28 (CD28 产品)
- 别名
- Tp44 antibody, CD28RNA antibody, cd28 antibody, CD28 molecule antibody, CD28 antigen antibody, Cd28 molecule antibody, CD28 molecule L homeolog antibody, CD28 antibody, Cd28 antibody, cd28.L antibody
- 背景
- CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Synonyms: T-cell-specific surface glycoprotein CD28, TP44
- 基因ID
- 940
- UniProt
- P10747
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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