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PPP6C 抗体 (N-Term)

This anti-PPP6C antibody is a 兔 多克隆 antibody detecting PPP6C in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN392922
发货至: 中国

Quick Overview for PPP6C 抗体 (N-Term) (ABIN392922)

抗原

See all PPP6C 抗体
PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))

适用

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  • 2
  • 2
  • 1
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宿主

  • 35
  • 3
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克隆类型

  • 35
  • 5
多克隆

标记

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This PPP6C antibody is un-conjugated

应用范围

  • 32
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB5866
  • 抗原表位

    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
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    • 1
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    AA 1-30, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PPP6C.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))

    别名

    PPP6C

    背景

    PPP6C belongs to the PPP phosphatase family, PP-V subfamily. Reversible phosphorylation of proteins on serine and threonine residues is an important biochemical event that regulates a broad variety of intracellular processes. The phosphorylation state is determined by the well-controlled balance of activities of serine/threonine-specific protein kinases and protein phosphatases, including PPP6C. Expression levels are highest in testis, heart, and skeletal muscle and lowest in placenta, lung, and kidney. PPP6C can complement mutations in the S. cerevisiae Sit4 and S. pombe ppe1 genes, indicating that PPP6C is the functional homolog of yeast Sit4p and ppe1. Since Sit4p is required for the G1 to S transition of the cell cycle and ppe1 is involved in cell shape control and mitotic division, it has been suggested that PPP6C functions in cell cycle regulation.

    分子量

    35144

    基因ID

    5536

    NCBI登录号

    NP_001116827, NP_001116841, NP_002712

    UniProt

    O00743
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