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PPM1F 抗体 (C-Term)

PPM1F 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5987 unconjugated
产品编号 ABIN392884
发货至: 中国
  • 抗原 See all PPM1F 抗体
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    抗原表位
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 409-439, C-Term
    适用
    • 49
    • 2
    • 1
    宿主
    • 42
    • 7
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 25
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPM1F antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 20
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PPM1F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human PPM1F.
    克隆位点
    RB5987
    亚型
    Ig Fraction
    Top Product
    Discover our top product PPM1F Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    别名
    PPM1F (PPM1F 产品)
    别名
    1110021B16Rik antibody, 4933427B07Rik antibody, CaMKPase antibody, Popx2 antibody, mKIAA0015 antibody, CAMKP antibody, FEM-2 antibody, POPX2 antibody, hFEM-2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1F antibody, protein phosphatase 1F (PP2C domain containing) antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1F antibody, PPM1F antibody, Ppm1f antibody
    背景
    PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.
    分子量
    49831
    基因ID
    9647
    NCBI登录号
    NP_055449
    UniProt
    P49593
    途径
    Positive Regulation of Endopeptidase Activity
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