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DUSP4 抗体 (C-Term)

DUSP4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB05733 unconjugated
产品编号 ABIN392861
发货至: 中国
  • 抗原 See all DUSP4 抗体
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    抗原表位
    • 16
    • 7
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-361, C-Term
    适用
    • 56
    • 39
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 4
    克隆类型
    • 52
    • 4
    多克隆
    标记
    • 23
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP4 antibody is un-conjugated
    应用范围
    • 43
    • 24
    • 20
    • 14
    • 13
    • 13
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This DUSP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human DUSP4.
    克隆位点
    RB05733
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP4 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    别名
    DUSP4 (DUSP4 产品)
    别名
    zgc:55423 antibody, DUSP4 antibody, typ antibody, hvh2 antibody, mkp2 antibody, mkp-2 antibody, MGC131045 antibody, HVH2 antibody, MKP-2 antibody, MKP2 antibody, TYP antibody, 2700078F24Rik antibody, AI844617 antibody, BB104621 antibody, E130306H24Rik antibody, Mkp-2 antibody, Mkp2 antibody, dual specificity phosphatase 4 antibody, dual specificity phosphatase 4 S homeolog antibody, dusp4 antibody, DUSP4 antibody, dusp4.S antibody, Dusp4 antibody
    背景
    DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
    分子量
    42953
    基因ID
    1846
    NCBI登录号
    NP_001385, NP_476499
    UniProt
    Q13115
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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