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Hexokinase 1 抗体 (N-Term)

HK1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3921-RB3922 unconjugated
产品编号 ABIN392759
发货至: 中国
  • 抗原 See all Hexokinase 1 (HK1) 抗体
    Hexokinase 1 (HK1)
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-108, N-Term
    适用
    • 87
    • 46
    • 32
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 95
    • 12
    克隆类型
    • 86
    • 21
    多克隆
    标记
    • 58
    • 17
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Hexokinase 1 antibody is un-conjugated
    应用范围
    • 86
    • 47
    • 38
    • 17
    • 17
    • 15
    • 11
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HK1 (Hexokinase) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-108 amino acids from the N-terminal region of human HK1 (Hexokinase).
    克隆位点
    RB3921-RB3922
    亚型
    Ig Fraction
    Top Product
    Discover our top product HK1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:2000. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Lynn, Wang, Markesbery, Lovell: "Quantitative changes in the mitochondrial proteome from subjects with mild cognitive impairment, early stage, and late stage Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 19, Issue 1, pp. 325-39, (2010) (PubMed).

  • 抗原
    Hexokinase 1 (HK1)
    别名
    HK1 (Hexokinase) (HK1 产品)
    背景
    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. The hexokinase gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of the hexokinase gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. HK1 encodes the ubiquitously expressed isoform. Its 5' end includes an exon which is unique to this transcript and which encodes a distinct N-terminus that contains the porin binding domain (PBD). The porin binding domain mediates association with the mitochondrial membrane.
    分子量
    102486
    基因ID
    3098
    NCBI登录号
    NP_000179, NP_277031, NP_277032, NP_277033, NP_277035
    UniProt
    P19367
    途径
    Carbohydrate Homeostasis, Warburg Effect
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