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DGKQ 抗体 (C-Term)

DGKQ 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB3823 unconjugated
产品编号 ABIN392717
发货至: 中国
  • 抗原 See all DGKQ 抗体
    DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
    抗原表位
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 912-942, C-Term
    适用
    • 28
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 27
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DGKQ antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 8
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DGKQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-942 amino acids from the C-terminal region of human DGKQ.
    克隆位点
    RB3823
    亚型
    Ig Fraction
    Top Product
    Discover our top product DGKQ Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
    别名
    DGKQ (DGKQ 产品)
    别名
    DAGK antibody, DAGK4 antibody, DAGK7 antibody, 110kDa antibody, Dagk4 antibody, Dgkd antibody, diacylglycerol kinase theta antibody, diacylglycerol kinase, theta antibody, diacylglycerol kinase, theta, putative antibody, DGKQ antibody, Dgkq antibody, Smp_163080 antibody, Tsp_13406 antibody
    背景
    Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid.The predicted 882-amino acid human DGKQ (DGK-theta) protein is 90 % identical in sequence to the rat homolog. DGK-theta is comprised of a pleckstrin homology domain and the conserved DGK putative catalytic domain. In contrast to other DGK isotypes, DGK-theta contains 3 rather than 2 cysteine-rich zinc-binding domains, an N-terminal proline- and glycine-rich region, and a RAS-associating domain. Highest tissue expression in the rat is in the brain. Defects in eye-specific DAGK genes cause retinal degeneration in Drosophila, thus, DAGK genes are candidates for human eye disease.
    分子量
    101155
    基因ID
    1609
    NCBI登录号
    NP_001338
    UniProt
    P52824
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