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SIK1 抗体 (C-Term)

SIK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3576 unconjugated
产品编号 ABIN392683
发货至: 中国
  • 抗原 See all SIK1 抗体
    SIK1 (Salt-Inducible Kinase 1 (SIK1))
    抗原表位
    • 16
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 567-597, C-Term
    适用
    • 73
    • 35
    • 23
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 73
    • 5
    克隆类型
    • 75
    • 3
    多克隆
    标记
    • 31
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIK1 antibody is un-conjugated
    应用范围
    • 57
    • 37
    • 15
    • 14
    • 7
    • 7
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SNF1LK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-597 amino acids from the C-terminal region of human SNF1LK.
    克隆位点
    RB3576
    亚型
    Ig Fraction
    Top Product
    Discover our top product SIK1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Cheng, Liu, Wang, Zou, Santiago, Garbitt, Gjoerup, Iglehart, Miron, Richardson, Hahn, Zhao: "SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis." in: Science signaling, Vol. 2, Issue 80, pp. ra35, (2009) (PubMed).

  • 抗原
    SIK1 (Salt-Inducible Kinase 1 (SIK1))
    别名
    SNF1LK (SIK1 产品)
    别名
    Msk antibody, Sik antibody, Snf1lk antibody, SIK2 antibody, SNF1LK antibody, MSK antibody, SIK antibody, salt-inducible kinase 1 antibody, salt inducible kinase 1 antibody, SIK1 antibody, Sik1 antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
    分子量
    84902
    基因ID
    150094
    NCBI登录号
    NP_775490
    UniProt
    P57059
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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