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ZAK 抗体 (AA 271-300)

ZAK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03313-03314 unconjugated
产品编号 ABIN392643
发货至: 中国
  • 抗原 See all ZAK 抗体
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    抗原表位
    • 15
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-300
    适用
    • 42
    • 33
    • 17
    • 2
    宿主
    • 52
    • 6
    克隆类型
    • 52
    • 6
    多克隆
    标记
    • 32
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZAK antibody is un-conjugated
    应用范围
    • 32
    • 25
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This MLKLAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human MLKLAK.
    克隆位点
    RB03313-03314
    亚型
    Ig Fraction
    Top Product
    Discover our top product ZAK Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Pescatore, Esposito, Draber, Walczak, Ursini: "NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II." in: Cell death & disease, Vol. 7, Issue 8, pp. e2346, (2017) (PubMed).

  • 抗原
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    别名
    MLKLAK (ZAK 产品)
    背景
    MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
    分子量
    91155
    基因ID
    51776
    NCBI登录号
    NP_057737, NP_598407
    UniProt
    Q9NYL2
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