UHMK1 抗体 (N-Term)
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- 抗原 See all UHMK1 抗体
- UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))
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抗原表位
- AA 1-30, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UHMK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KIST (KIS).
- 克隆位点
- RB3367
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UHMK1 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).
: "PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2." in: Investigative ophthalmology & visual science, Vol. 52, Issue 1, pp. 417-26, (2011) (PubMed).
: "Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity." in: Investigational new drugs, Vol. 28, Issue 4, pp. 381-91, (2010) (PubMed).
: "Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation." in: The Journal of biological chemistry, Vol. 285, Issue 9, pp. 6585-94, (2010) (PubMed).
: "The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia." in: Carcinogenesis, Vol. 31, Issue 11, pp. 2012-21, (2010) (PubMed).
: "FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 453-60, (2007) (PubMed).
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Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).
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- 抗原
- UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))
- 别名
- KIST (KIS) (UHMK1 产品)
- 别名
- UHMK1 antibody, zgc:153241 antibody, KIS antibody, KIST antibody, P-CIP2 antibody, 4732477C12Rik antibody, 4930500M09Rik antibody, AA673513 antibody, AI449218 antibody, AU021979 antibody, Kist antibody, U2AF homology motif kinase 1 antibody, U2AF homology motif (UHM) kinase 1 antibody, UHMK1 antibody, uhmk1 antibody, Uhmk1 antibody
- 背景
- Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
- 分子量
- 46546
- 基因ID
- 127933
- NCBI登录号
- NP_001171692, NP_653225, NP_787062
- UniProt
- Q8TAS1
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